| 번호 |
물질 |
독성자료가 있는 동물종 |
| 1 |
Acacia |
Nonhuman primate, rat |
| 2 |
Acetate buffer |
Nonhuman primate, minipig, mouse, rat |
| 3 |
Acetic acid |
Dog, mouse, rat |
| 4 |
Acetone |
Guinea pig, mouse, rabbit, rat |
| 5 |
Acetonitrile |
Dog |
| 6 |
Acetylated lanolin alcochol |
Minipig |
| 7 |
Acetylmethylamide |
Nonhuman primate |
| 8 |
Alcohol denatured SDA |
Minipig |
| 9 |
Alginic acid |
Rat |
| 10 |
Anecortave acetate |
Rat |
| 11 |
Antifoam 1510-USTM |
Rat |
| 12 |
Avicel CL-611TM |
Dog |
| 13 |
Balanced salt saline |
Rabbit |
| 14 |
Basal salt solution |
Mouse |
| 15 |
Benzonic acid |
Rat |
| 16 |
Benzyl alcohol |
Cat, Dog, nonhuman primate, rat |
| 17 |
β-Cyclodextrin |
Dog, mouse, nonhuman primate, rat |
| 18 |
BHA |
Minipig |
| 19 |
BHT |
Cat, Dog, nonhuman primate, rat |
| 20 |
Bicarbonate buffer |
Mouse |
| 21 |
Calcium chloride |
Mouse |
| 22 |
Canola oil |
Dog |
| 23 |
Capmul MCMTM |
Nonhuman primate |
| 24 |
Capmul MCM NFTM |
Dog, rat |
| 25 |
Capmul PG 8TM |
Dog, rat |
| 26 |
Capryol 90TM |
Dog, rabbit, rat |
| 27 |
CaptisolTM |
Dog, mouse, nonhuman primate, rat |
| 28 |
Carbomer 974PTM |
Minipig, mouse |
| 29 |
Carbopol Ultrez 10TM |
Minipig |
| 30 |
Carboxymethylcellulose |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
| 31 |
Carboxymethylcellulose calcium |
Dog |
| 32 |
Carboxymethylcellulose sodium |
Mouse, rabbit, rat |
| 33 |
CavisolTM |
Dog, rat |
| 34 |
Cetostearyl alcohol |
Minipig |
| 35 |
Cetyl acetate |
Minipig |
| 36 |
Cetyl alcohol |
Minipig, mouse |
| 37 |
Citrate buffer |
Dog, nonhuman primate, rat |
| 38 |
Citric acid buffer |
Cat, dog, nonhuman primate, rat |
| 39 |
Coconut oil |
Minipig |
| 40 |
Collagen matrix |
Nonhuman primate, rabbit |
| 41 |
Corn oil |
Chicken embryo, dog, mouse, nonhuman primate, rabbit rat |
| 42 |
Cottonseed oil |
Dog |
| 43 |
Cyclodextrin |
Rat |
| 44 |
Cyclohexane |
Rabbit, rat |
| 45 |
Cyclomethicone NF |
Minipig |
| 46 |
DAM |
Dog, rat |
| 47 |
Dextrose |
Cat, dog, minipig, nonhuman primate, rabbit, rat |
| 48 |
Dichlorvos |
Nonhuman primate |
| 49 |
Diethylacetamide |
Cat, chicken, dog, mouse, rabbit, rat |
| 50 |
Diethylene glycolmonoethyl ether |
Nonhuman primate |
| 51 |
Dimethicone |
Rabbit |
| 52 |
Dimethiconol blend 20 |
Minipig |
| 53 |
Dimethylacetamide |
Chicken, dog, mouse, rabbit, rat |
| 54 |
Dimethyl sulfoxide |
Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat |
| 55 |
Disodium hydrogen phosphate dihydrate |
Nonhuman primate |
| 56 |
Docosanol |
Minipig |
| 57 |
Dulbecco's modified PBS |
Rat |
| 58 |
Dulbecco's PBS |
Rat |
| 59 |
EDTA |
Minipig, nonhuman primate, rat |
| 60 |
Ethanol |
Dog, guinea pig, minipig, mouse, nonhuman primate, rat |
| 61 |
Fumaric acid |
Dog |
| 62 |
Gelatin |
Dog, nonhuman primate, |
| 63 |
Gelatin phosphate buffer |
Minipig |
| 64 |
GelucireTM |
Minipig |
| 65 |
Gelucire 44/14TM |
Dog, minipig, mouse, rabbit, rat |
| 66 |
Gelucire 50/13TM |
Rat |
| 67 |
Gluconic acid |
Dog, rat |
| 68 |
Glycerol |
Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat |
| 69 |
Glyceryl stearate SE |
Minipig |
| 70 |
Glycofurol |
Dog |
| 71 |
Glycol dimethacrylate crosspolymer |
Rat |
| 72 |
Gum tragacanth |
Mouse |
| 73 |
Gum xanthan |
Minipig, rabbit, rat |
| 74 |
Hexylene glycol |
Minipig |
| 75 |
Histidine |
Dog, rat |
| 76 |
Hydrochloric acid |
Dog, rat |
| 77 |
Hydrogenated castor oil |
Minipig |
| 78 |
Hydroxyethylcellulose |
Rat |
| 79 |
Hydroxypropyl β-cyclodextrin |
Dog, mouse, nonhuman primate, rat |
| 80 |
Hydroxypropyl cellulouse |
Minipig, rat |
| 81 |
Hydroxypropyl methylcellulose |
Dog, minipig, mouse, nonhuman primate, rat |
| 82 |
Hydroxypropyl methylcellulose acetate succinate |
Dog, minipig, mouse, rabbit, rat |
| 83 |
Hymetellose |
Rabbit |
| 84 |
Hypotonic PBS |
Dog, rat |
| 85 |
Imwitor 742TM |
Hamster, nonhuman primate, rat |
| 86 |
Isopropyl alcohol |
Dog, rabbit |
| 87 |
Isopropyl myristate |
Minipig, mouse, rabbit |
| 88 |
Isotonic saline |
Rat |
| 89 |
KolliphorTM |
Nonhuman primate |
| 90 |
Kolliphor ELTM |
Dog, mouse, nonhuman primate, rat |
| 91 |
Kolliphor ELPTM |
Dog |
| 92 |
Kolliphor HS15TM (see also Solutol HS15) |
Minipig |
| 93 |
Kolliphor RH40TM |
Dog, rat |
| 94 |
Labrafil M1944TM |
Dog, rabbit, rat |
| 95 |
LabrasolTM |
Dog, minipig, rabbit, rat |
| 96 |
Lactated Ringer's |
Nonhuman primate |
| 97 |
Lactic acid |
Dog, rat |
| 98 |
Lactose |
Dog, nonhuman primate, rat |
| 99 |
Lanolin |
Minipig, rabbit |
| 100 |
Lanolin alcohol NF |
Minipig |
| 101 |
L-Arginine HCl USP |
Minipig, nonhuman primate |
| 102 |
L-Ascorbic acid |
Rat |
| 103 |
Lauroglycol 90TM |
Rabbit, rat |
| 104 |
Maltitol solution |
Rat |
| 105 |
Maltol |
Guinea pig, rabbit |
| 106 |
Mannitol |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
| 107 |
Methanesulfonic acid |
Rat |
| 108 |
MethocelTM |
Nonhuman primat, rat |
| 109 |
Methyl methacrylate |
Rat |
| 110 |
Methylcellulose |
Dog, guinea pig, mouse, nonhuman primate, rabbit, rat |
| 111 |
Methylparaben |
Minipig |
| 112 |
Methylpyrrolidone |
Dog, minipig, mouse |
| 113 |
Mineral oil |
Cat, dog, guinea pig, minipig, mouse, rat |
| 114 |
Myristyl alcohol |
Minipig |
| 115 |
Neobell 1053 OilTM |
Mouse, rat |
| 116 |
Octoxynol-40 |
Dog, rabbit |
| 117 |
Oleic acid NF |
Minipig |
| 118 |
Oleyl alcohol NF |
Minipig |
| 119 |
Olive oil |
Minipig, rat |
| 120 |
Ora-PluseTM suspension |
Rat |
| 121 |
Panthenol |
Minipig |
| 122 |
Peanut oil |
Dog, rat |
| 123 |
Peceol |
Dog, rat |
| 124 |
PEG 200 |
Minipig, nonhumand primate, rabbit, rat |
| 125 |
PEG 300 |
Cat, dog, guinea pig, mouse, rabbit, rat |
| 126 |
PEG 400 |
Dog, guinea pig, minipig, mouse, nonhuman primate, minipig, rabbit, rat |
| 127 |
PEG 600 |
Rat |
| 128 |
PEG 810 |
Rat |
| 129 |
PEG 1000 |
Mouse, rabbit, rat |
| 130 |
PEG 1500 |
Rat |
| 131 |
PEG 1540 |
Dog, rabbit, rat |
| 132 |
PEG 4000 |
Dog, mouse, rabbit, rat |
| 133 |
PEG 6000 |
Rabbit, rat |
| 134 |
PEG 10000 |
Rat |
| 135 |
PEG 400000 |
Rat |
| 136 |
Petrolatum |
Rabbit |
| 137 |
Phenoxyethanol |
Minipig, mouse |
| 138 |
Phosal 53 MCTTM |
Rat |
| 139 |
Phosphate |
Nonhuman primate |
| 140 |
Phosphate buffer |
Rat |
| 141 |
Phosphate-buffered saline |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
| 142 |
Polawax |
Minipig, mouse |
| 143 |
Poloxamer 124TM |
Dog, mouse, rat |
| 144 |
Poloxamer 188TM |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
| 145 |
Polyethylene terephthalate |
Rat |
| 146 |
Poly(glycolide-co-DL-lactide) microspheres |
Dog |
| 147 |
Polyglyceyl oleate |
Rabbit, rat |
| 148 |
Polyvinylpyrrlidone |
Dog, nonhuman primate, rabbit, rat |
| 149 |
Potassium chloride |
Minipig |
| 150 |
Propylene glycol |
Dog, minipig, puinea pig, nonhuman primate, mouse, rabbit, rat |
| 151 |
Propylene glycol dicaprylate/dicaprate |
Rat |
| 152 |
Propylparaben |
Minipig |
| 153 |
PVP VA 64 |
Dog, rat |
| 154 |
RAMEB |
Nonhuman primate |
| 155 |
Safflower oil |
Dog |
| 156 |
Salicylic acid |
Minipig |
| 157 |
Saline(pH adjusted, pH 4.5) |
Dog, mouse, rabbit, rat |
| 158 |
Sesame oil |
Minipig |
| 159 |
Shea butter |
Rat |
| 160 |
Simethicone |
Dog, mouse, nonhuman primate, rat |
| 161 |
Sodium acetate trihydrate buffer |
Mouse, nonhuman primate |
| 162 |
Sodium chloride |
Cat, dog minipig, mouse, nonhuman primate, rabbit, rat |
| 163 |
Sodium citrate |
Nonhuman primate, rat |
| 164 |
Sodium dihydrogen phosphate dihydrate |
Mouse, nonhuman primate |
| 165 |
Sodium hydroxide |
Minipig, mouse, nonhuman primate, rat |
| 166 |
Sodium lauryl sulfate |
Dog, rat |
| 167 |
Sodium metabisulfite |
Mouse, nonhuman primate, rat |
| 168 |
Sodium methylparaben |
Minipig, mouse, rat |
| 169 |
Sodium phosphate buffer |
Dog, mouse, nonhuman primate, rat |
| 170 |
Sodium propylparaben |
Mouse, rat |
| 171 |
Sodium succinate |
Dog, mouse rat |
| 172 |
Sodium sulfite |
Rabbit |
| 173 |
Solutol HS15TM(see also Kolliphor HS15TM) |
Dog, mouse, nonhuman primate, rat |
| 174 |
Sorbitan tristearate |
Minipig |
| 175 |
Sorbitol |
Dog, nonhuman primate, rat |
| 176 |
Soybean oil |
Dog, minipig, rat |
| 177 |
Squalane NF |
Minipig |
| 178 |
Stearic aicd |
Minipig |
| 179 |
Steayl alcohol |
Minipig |
| 180 |
Sucrose |
Cat, dog, nonhuman primate, rabbit, rat |
| 181 |
Sucrose acetate isobutyrate |
Cat |
| 182 |
Sulfobutyl ether β-cyclodextrin |
Mouse |
| 183 |
Tartaric acid |
Rabbit, rat |
| 184 |
Terbinafine HCLTM placebo nail lacquer |
Pig |
| 185 |
Tetraglycol |
Minipig, rat |
| 186 |
TranscutolTM |
Cat, dog, guinea pig, minipig, mouse, rabbit, rat |
| 187 |
Trehalose |
Dog, rat |
| 188 |
Tris buffer |
Minipig, nonhuman primate |
| 189 |
Trisodium citrate dihydrate |
Dog, hamster, mouse, rat |
| 190 |
Tween 20TM |
Dog, minipig, mouse, nonhuman primate, rat |
| 191 |
Tween 80TM |
Dog, guinea pig, hamster,minipig, mouse, nonhuman primate, rabbit, rat |
| 192 |
Vitamin E |
Dog, rabbit, rat |
| 193 |
Vitamin E TPGS |
Dog, mouse, rabbit, rat |
| 194 |
Water(Note: only combination formulations expressly listing water in their ingredients are listed here) |
Dog, guinea pig, minipig, mouse, nonhuman primate, pig, rabbit, rat |
| 195 |
White wax |
Minipig |
| 196 |
Xylitol |
Nonhuman primate |
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